Adderall is a combination medicine that is designed to treat attention deficit hyperactive disorder (ADHD) in children and adults. Adderall can improve attentiveness and alertness, and may improve behavior issues. Adderall contains amphetamine and dextroamphetamine salts and is a Schedule IIN substance in the United States, meaning that it is a narcotic that has a medical use, but also has high potential for abuse and physical and psychological dependence.[1]
In March 2021 the U.S. Drug Enforcement Agency issued a warning for the New England region stating that counterfeit Adderall pills being circulated throughout New Hampshire contain the highly addictive drug methamphetamine.[2] The pills are purposely manufactured to appear the same as real Adderall tablets, including matching the color of the pill and the proprietary markings.
The TacticID Mobile® handheld Raman system from B&W Tek employs a 1064 nm laser, and can be used to quickly identify illicit substances in the field with the push of a button. The TacticID Mobile is able to suppress fluorescence and can identify more substances than traditional 785-nm Raman systems.
In this case study, a suspected counterfeit Adderall pill was measured with a TacticID Mobile and a traditional 785-nm handheld Raman system. The pill was measured directly using a point-and-shoot adapter on both systems.
Figure 1 shows the spectrum of the suspected counterfeit pill measured with a 785-nm handheld Raman system. The spectrum is overwhelmed by fluorescence, and the system does not yield any match to the library.
The counterfeit Adderall tablet was then measured on the TacticID Mobile. The result returned was a mixture of cellulose and caffeine, another stimulant not used in the manufacturing of Adderall (Figure 2).
Figure 3 shows the spectral comparison of the suspected counterfeit pill and a confirmed Adderall pill found to contain lactose, the main excipient in the pill.
With its state-of-the-art fluorescence suppression, the TacticID Mobile gives those on the front lines a tool in the fight against dangerous counterfeit drugs.
- U.S. Department of Justice/Drug Enforcement Agency Diversion. Control Division. Controlled Substance Schedules. https://www.deadiversion.usdoj.gov/schedules/ (accessed April 2021)
- WMUR9. Methamphetamine pills designed to look like Adderall found across New Hampshire. https://www.wmur.com/article/methamphetamine-pills-designed-to-look-like-adderall-found-across-new-hampshire/35867602 (accessed April 2021)