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AN-NIR-066

Content uniformity of pharmaceutical solid dosage forms using Vis-NIR spectroscopy examplified on cefixime tablets


Summary

Determination of the API (active pharmaceutical ingredient) content in medications is critical for pharmaceutical producers to adhere to regulations and ensure consumer safety. Testing is normally done with high performance liquid chromatography (HPLC), although this method is costly, time-consuming, and requires highly skilled laboratory personnel. A cost-effective, faster option is visible-near-infrared spectroscopy (Vis-NIRS). This Application Note presents Vis-NIR spectroscopy as a viable alternative to determine API content in cefixime tablets without sample preparation.

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Metrohm USA

9250 Camden Field Pkwy
33578 Riverview, FL

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